Drug-Drug Interactions:Inform the doctor if you are taking phenothiazine (thioridazine), anti-psychotic (lithium), antibiotic (linezolid, telithromycin, erythromycin, clarithromycin), an amino acid (tryptophan), pain killer (tramadol, ibuprofen, aspirin), anti-HIV (ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir, fosamprenavir), anti-fungal (ketoconazole, itraconazole, fluconazole), anti-depressant (nefazodone), blood thinner (warfarin), impotent agents (sildenafil, tadalafil, vardenafil), calcium channel blocker (diltiazem, verapamil), anti-emetics (aprepitant), BPH agents and anti-migraine medicines.
Drug-Food Interactions:Do not take St. John’s wort (herbal supplement used to treat depression) while taking Dapoxetine. Avoid consuming grapefruit juice within 24 hours of taking Dapoxetine as it could lead to an increase in the level of Dapoxetine in the body.
Drug-Disease Interactions:Inform the doctor if you have cardiovascular/heart disease, a history of dizziness due to low blood pressure, depression, mania, bipolar disorder, schizophrenia, epilepsy/fits, bleeding or blood clotting problems, glaucoma, kidney problems, or moderate to severe liver problems.
Appropriate medical advice is required from the patient regarding the use of this medication. Without medical advice, do not take Dapoxetine.Appropriate medical advice is required is there is any information regarding diseases accompanied with use of this medication. The patient should be aware of the warning signs of this medication, including skin rash, itching/swelling (especially of the face/tongue/throat), dizziness, lightheadedness, blurred vision, heartburn, nausea, and the presence of food in the mouth. Do not use if the symptoms persist for more than 1 day unless directed by the doctor.
Precautions If you are allergic to St John's wort, or any of its ingredients, you should avoid Dapoxetine. Avoidance should be exercised in pregnancy and lactation.Appropriate medical advice is required is there alternative medication is not recommended. Do not stop taking Dapoxetine suddenly without consulting your doctor.Do not stop taking Dapoxetine without consulting your doctor.Precautions If you are suffering from a mental health condition or suffering from any other condition, you should avoid using this drug. For example, you might avoid having thoughts, feelings or activities that you might be experiencing or might cause you to feel anxious, depressed, trouble sleeping, or experience any other psychological condition, especially thoughts of suicide. You should avoid using the drug if you are allergic to the ingredients.
Precautions If you are pregnant or breast-feeding, avoid driving or operating machinery until you know how St John's wort will affect you. This medication may cause changes in the menstrual periods of a man. Do not take the drug if you are pregnant or breast-feeding.
Precautions If you have depression, you might avoid having thoughts, feelings or activities that you might be experiencing or might cause you to feel anxious, depressed, trouble sleeping, experience any other psychological condition, especially thoughts of suicide.
A: Take Duralast at least 1–3 hours before anticipated sexual activity.
A: Studies tell, after three months of men taking 30 mg dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration.
A: There is no permanent cure for premature ejaculation (PE), but there are treatments that can help. Some treatments include medications, counselling and techniques.
A: No. Duralast is not recommended for use in patients with heart problems (such as a heart attack or abnormal heart rhythm).
A: Duralast should be used with caution in patients with kidney diseases.
Viagra enhances blood flow to the penis, which helps in achieving and sustaining an erection. Dapoxetine helps to delay ejaculation by increasing serotonin levels in the brain, which improves control over the timing of ejaculation.
A: Consult your doctor before taking Duralast and Viagra together, as they may lower your blood pressure, especially when standing up.
A: Duralast should only be used if you are diagnosed with premature ejaculation. It is not intended for regular daily use.
A: Duralast is not recommended if you are allergic to it, men who are below 18 years or above 65 years. It is not intended for use in women. Avoid consuming alcohol as it might cause increased dizziness.
A: The mean half life of dapoxetine after a single dose was estimated using modelling as 1.3–1.5 hours.
A: Take dapoxetine exactly as instructed by your doctor. Drink a full glass of water at the same time as you take a tablet.
A: Dapoxetine is available at 2 different strengths such as 30 mg and 60 mg. The recommended starting dose for all men is 30 mg, taken as needed approximately 1 to 3 hours prior to sexual activity.
A: Dapoxetine is used for premature ejaculation (PE) in men between 18 to 64 years old.
A: Men taking a 30 mg dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration, those on a 60 mg dose took 3.32 minutes.
A: Men release quickly due to premature ejaculation, nervousness of being with a new partner, anxiousness of having sex again after a long period of abstinence, lack of confidence, guilt, being overly excited or stimulated or other reasons.
Add to Edit Online Date 12 Mar 2025Duralast is a combination medicine containing 30 mg dapoxetine or dapoxetine HCl, which belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs).
Dapoxetine+sildenafil is an oral drug used to treat premature ejaculation in men 18 and up. This helps to prolong ejaculation, which can last for up to 6 hours, before it goes away. This is similar to what men with erectile dysfunction will use to treat their urinary tract problems.
Premature ejaculation can cause problems in men’s sexual health. It can also have a serious impact on relationships and mental well-being.
If you want to improve your sexual health, you can use Dapoxetine+sildenafil to help you achieve a harder, longer-lasting erection. This is because Dapoxetine+sildenafil works by blocking the action of an enzyme called PDE5. This enzyme can increase the amount of blood that comes in contact with the penis.
The recommended starting dose of Dapoxetine+sildenafil is 30 mg. You can take this tablet with or without food. However, if it ups the dose, make sure to take it on an empty stomach. The tablet should be swallowed whole with a glass of water. Take Dapoxetine+sildenafil at the same time daily, with or without food. You can take this tablet up to 4 hours before the sexual activity.
Do not take more than one tablet in 24 hours. Do not take this tablet more than once a day.
Like all medicines, Dapoxetine+sildenafil can cause side effects. Although not everybody gets them, some common side effects of Dapoxetine+sildenafil include:
If you experience any of the following serious side effects, stop taking Dapoxetine+sildenafil and seek medical attention immediately:
No, Dapoxetine+sildenafil doesn’t cause permanent side effects. However, you may experience other effects, such as allergic reactions, chest pain, irregular heartbeat, or changes in the sex drive.
Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.
Nitroprusside sodium
The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.
Enzalutamide
Use alternative drugs because the use of enzalutamide will decrease the effect of sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
Acetazolamide
Therapy should be administered with caution because the use of acetazolamide will increase the effect of sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.
Cardiovascular disease:
The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.
Renal dysfunction:
Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.
Liver diseases:
The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.
Addictive (patent) or not available?No, this medicine is not sold under the same brand name. Therefore, the customer must choose the brand of product who supplied the product.
AddictionDo not use this medicine if you are also using or have taken an existing drug.
Disclaimer of!Every product published onowder is for research and management. Please consult your doctor before making any changes.
unveilingContraindications
This medication does not affect the workingmen’s role or the role of the patient in bed. It only affects the patient in a patient’s presence.
Special warnings
Special advice
The vision loss specialist should stop dapoxetine and prescribe a retinoids drug.
Salt Composition in both
Salt Composition
Dapoxetine 30mg(same for both)
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Cipla Tablet 15s contains Disulfiram, EpoDerm 15, and Disulfiram + Minoc Dictionary 15. Cipla Tablet 15s contains Disulfiram + EpoDerm 15 and Disulfiram + Minoc Dictionary 15 are FDA-approved medications used to treat erectile dysfunction (ED). Cipla Tablet 15s contains EpoDerm 15 and EpoDerm 15 are FDA-approved medications used to treat premature ejaculation (PE). The medication is FDA-approved to treat PE and is used to treat ED.
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